Jyothi nvn, prasanna pm, sakarkar sn, prabha ks, ramaiah ps, srawan gy 2010 microencapsulation techniques, factors influencing encapsulation efficiency. Obtaining, handling, and storing of explosives, especially primaries such as triacetonetriperoxide tatp, presents significant obstacles to instrument manufacturers and k9 trainers. Encapsulation efficiency ee was determined according to the method described by bae and lee 2008. This is achieved by thorough characterization, both before and after microsphere fabrication. One of the highly efficient method is microencapsulation. The optimization of the liposomal encapsulation of a drug is usually based on trial and error, rather than on a thorough investigation of the factors affecting it. Is there a difference between microencapsulation and. Additional aspects of encapsulation to be discussed include materials, process scale, and application examples. Microencapsulation, method, process, variables introduction 12 control drug delivery, using biodegradable polymer. The dependence so many process variables may become a problem in terms of reproducibility and scaleup process. One of the largest food applications is the encapsulation of flavours shahidi and han, 1993.
Pdf microencapsulation techniques and its practices. African journal of food science drying by spray drying. Additionally, other factors influence the release, such as the volatility of the. The effects of factors involved in microencapsulation processes, on the efficiency and quality of the produced innovative microcapsules were also discussed and highlighted. Encapsulation is typically tied to spray drying, a form of nutrient protection that typically involves. However, its inadequate volatile characteristics made it less efficient. Health related nutrients for pharmaceutical delivery packing active ingredients into a hard shell or soft gel capsule 10 mm long to preserve. Three levels of each variable and four repetitions at the center point, giving a.
Jyothi nvnp, prasanna m, sakarkar sn, prabhal s, srawan gy 2010. Microencapsulation an overview sciencedirect topics. In general, it is used to incorporate food ingredients, enzymes, cells or other materials on a micro metric scale. Microencapsulation techniques, factors influencing encapsulation efficiency 195 journal of microencapsulation downloaded from by hinari on. Microencapsualtion techniques, factors influencing encapsulation efficiency. In this technique, the core melting temperature must be higher than the shell melting temperature. Factors influencing encapsulation efficiency of biologically active compound into pla submicroparticles stloukal petr2, koutny marek1,2, sedlarik vladimir1, pavel kucharczyk1 1centre of polymer systems, tomas bata university in zlin, nam. Major common encapsulation techniques and formulations will be presented, along with examples, equipment, strengths, weaknesses, and state of the art. Encapsulation efficiency and oxidative stability of. Development of thermoregulating textile materials with microencapsulated phase change materials iv. Our diverse, extensive encapsulation methods solve product performance requirements for clients. Microencapsulation techniques, factors influencing encapsulation efficiency 189 journal of microencapsulation downloaded from by hinari on 060510 for personal use only. Many microencapsulation methods were conducted for varies essential oils. The method of preparation and the techniques employed for microencapsulation overlap considerably fig.
Microencapsulation can also be used to enclose solids, liquids, or gases inside a micrometric wall made of hard or soft soluble film. Microencapsulation, encapsulation efficiency, coacervation, coating materials. Detection of most explosive vapor is a challenge for. Abstractmicroencapsulation is finding increasing applications in cosmetics and personal care markets. Nano and microencapsulation using food grade polymers. This article provides an overall discussion on encapsulation of cosmetically active ingredients and encapsulation techniques for cosmetic and personal care products for topical applications.
Essential oil contained volatile compounds and they are benefit in many fields such as pharmaceutical, flavor, perfume, food, agriculture, and detergent. Ghosh sk 2006 functional coatings and microencapsulation. Introduction microencapsulation is a process by which very tiny. Jyothi n, nagavp, muthu p, suhas ns, sakarkar k, et al. Project developers and formulators often use microencapsulation and encapsulation interchangeably. The various microencapsulation processes can be divided into chemical, physiochemical, and electrostatic and mechanical processes. Low encapsulation efficiency value could be due to.
The encapsulation efficiency of the microparticle or microsphere or microcapsule depends upon different factors like concentration of the polymer, solubility of. According to finch, the main methods of micro encapsulation can be classified as follows. Microencapsulation techniques, factors influencing encapsulation efficiency. Microencapsulation properties of gum arabic and several food proteins. The encapsulation efficiency of the microparticle or microsphere or microcapsule depends upon different factors like concentration of the polymer, solubility of polymer in solvent, rate of solvent removal, solubility of organic solvent in water, etc. Microspheres efficiently utilized in controlled delivery of many drugs but wastage of drug due to low drug entrapment efficiency is the major drawback of such microparticulate system. Brazilian archives of biology and technology print version issn 151689online version issn 16784324. Article pdf available january 2008 with 2,121 reads. Significant effects of the tlc were found on the product yield, encapsulation efficiency, thermal stability, morphology, and on the particle size distribution. The experimental data obtained of the encapsulation efficiency and loading capacity of the particles were adjusted to the secondorder polynomial model. Microencapsulation is a process in which tiny particles or droplets are surrounded by a coating to give small capsules, of many useful properties. Factors affecting microencapsulation of drugs in liposomes. Internet scientific publications microencapsulation techniques, factors influencing encapsulation efficiency.
Figure 3factors influencing encapsulation efficiency jyothi et al. The choice of microencapsulation method very much affected by the material to be encapsulated. But the difference between the two is considerable. Many factors affect the quality of microcapsules, including preparation. Microencapsulation is a rapidly expanding technology in which very tiny droplets or particles of liquid or solid material are surrounded or coated with a continuous film of polymeric material1. A brief focus has been finally addressed to new insights and additional knowledge on micro. Some of the challenges are identified and critical aspects and future perspectives are. The encapsulation efficiency of the microparticle or microsphere or microcapsule depends upon different factors like concentration of the polymer, solubility of polymer in solvent, rate of solvent removal, solubility of organic solvent in water etc. Microencapsulation may be defined as the packaging technology of solids, liquid. Pdf application of polymer systems to the detection and.
Chemical processes include the interfacial and in situ polymerization methods. For the love of physics walter lewin may 16, 2011 duration. Issn 2249 1023 microencapsulation a novel approach in. Airsuspension coating microencapsulation by air suspension is a technique that gives. Microencapsulation methods of volatile essential oils a. Microencapsulation, microcapsules, self assembling structures. Microencapsulation are involved in converting liquids to. Performance properties and hand of fabrics treated with pcm.
The techniques used to produce these capsules range from simple blend operations to complex polymeric coating systems. Coacervation phase separation techniques authorstream. Microencapsulation as a delivery system has proved itself useful in a variety of commercial applications in many areas of industry. Microencapsulation techniques, factors influencing encapsulation efficiency nvn jyothi, pm prasanna, sn sakarkar, ks prabha, ps ramaiah. Introduction microencapsulation is the process of enclosing a. There are different techniques available for the encapsulation of drug entities. Our team can help solve product stability such as release and application problems for a wide range of industries. Pdf microencapsulation techniques, factors influencing. Influence of process conditions on powder property and dryer. This is the first study regarding the encapsulation of tyrosol and brings new insights concerning the encapsulation of antioxidants for further incorporation in food matrices. Encapsulation efficiency, the internet journal of nanotechnology, 2009 volume 3, number 1, issn.
The systems discussed in this chapter provide only a brief introduction to the world of microencapsulation and its potential applications. New trends in the microencapsulation of functional fatty. Microencapsulation techniques, factors influencing encapsulation. Microencapsulation techniques, factors influencing. Swri scientists continue to develop and discover diverse microencapsulation techniques for pharmaceuticals, food and nutrition, polymer and materials science, and process engineering. Microencapsulation, core materials, coating materials.
Comparison of the encapsulation efficiency of the drug in liposomes with the therapeutic dose indicates whether, in principle, liposomes can be used as a delivery system for that drug. Microencapsulation is used to modify and delayed drug release form pharmaceutical dosage forms. Microencapsulation techniques were used to trap tatp in a plastic matrix rendering it safe to handle, store at room temperature, and release by heating. Microencapsulation technique by solvent evaporation method.
565 62 119 943 187 686 236 1410 337 1258 1060 104 1118 1065 329 1265 1315 1122 298 88 822 1318 150 286 862 1009 1265 159 614 159 385 490 933 499 466 572 826 240 180